HER2T

Understand · Simulate · Discover

Autonomous Discovery

Command Center Discovery Console Hypothesis Ledger Knowledge Graph Agent Organization

Discovery Journey

Research Missions Validation Funnel Blinded Benchmark Quantitative Benchmark

Digital Protein Twin

Twin Overview Conformational States Experimental Evidence Twin Comparison Contradiction Log Curiosity Loop Investigation Loop

Digital Protein Foundry

Foundry Overview Model Candidates Model Arena Model Evolution Missing Variables

Idea Sieve

Sieve Overview Run Console Survivors & Lineage Rejection Analytics Learning Loop

Meta-Cognition

Meta Overview Run Bake-Off Cognition Stable Challenges Learned Policy Artifacts

Reference Data

Protein Explorer Mutation Database Drug-Protein Binding Simulations Research Feed Data Integration

Data Sources

UniProt • PDB • PubMed

Idea Sieve — Survivors

Surviving candidates & their lineage

Every survivor carries a full provenance trail: the grammar rule that generated it, the Twin uncertainty it targets, which gates it passed, which agents modified it, and — if escalated — its blinded prediction against held-out evidence.